'Simple biochemical theories that link low levels of serotonin with depressed mood are no longer tenable. '
Philip J Cowen and Michael Browning
University Department of Psychiatry, Warneford Hospital, Oxford, OX3 7JX, UK
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471964/
Εχουν προταθεί 3 νεες θεωριες σε αντικατασταση της παλιας αλλα παραμενουν θεωριες:
An initial computational account of serotonergic transmission suggested that it acted in opponency to dopamine, transmitting a “punishment prediction error”.
A second variant of this model frames the role of serotonin as controlling “delay-discounting”,
A third computational model, developed by Dayan and Huys , may be more relevant to the role of serotonin in depression and its treatment. Here, serotonin is perceived as influencing the way that one thought leads to another, specifically by inhibiting chains of thoughts predicted to lead to negative affective states (“let's not go there”). From this viewpoint, the role of serotonin is to ensure that thoughts with potentially negative emotional consequences are relatively underexplored; hence facilitation of serotonin produces a bias towards optimistic valuations, as rewarding thoughts are “visited” more frequently than punishing thoughts.
Dayan P, Huys QJM. Serotonin, inhibition, and negative mood. PLoS Comput Biol. 2008;4 [PMC free article] [PubMed]
Daw N, Kakade S, Dayan P. Opponent interactions between serotonin and dopamine. Neural Networks. 2002;15:603–16. [PubMed]
Cools R, Nakamura K, Daw ND. Serotonin and dopamine: unifying affective, activational and decision functions. Neuropsychopharmacology. 2011;36:98–113. [PMC free article] [PubMed]
Daw ND, Doya K. The computational neurobiology of learning and reward. Curr Opin Neurobiol. 2006;16:199–204. [PubMed]
Αυτά όλα είναι στην κρίση, λογική και συνείδηση του κάθε ενός. Το τι θα καταλάβει κάποιος απο αυτο το βίντεο, τι θα πιστέψει, τι θα υποστηρίξει και τι θα αμφισβητήσει και πόση προσοχή θα δώσει ή δεν θα δώσει.